Señor de Grajal. Virrey y Capitán General de Navarra en 1542-1543. Posteriormente, embajador en Roma (1543-1547) y virrey de Sicilia (1547-1557). En 1564 pasa a ocupar el virreinato de Cataluña. Fue comendador de Hornachos de la Orden de Santiago y presidente del Consejo de Castilla.
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